Jorjani Biomedicine Journal

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Diabetes is one of the main reasons for pathogenicity, death and increase in the cost of health services all over the world, and in case it occurs simultaneously with depression, the extent and severity of the symptoms will increase, as depression is one of the most prevalent psychological disorders in diabetic people which can result in more undesirable changes in the prognosis of the disease. Therefore, this study was conducted to determine the simultaneous incidence of diabetes and depression and some related issues. This

The incidence of depression together with diabetes causes a decrease in metabolic control, medication adherence, decreased quality of life, failure to follow appropriate diets, increase in the costs of health care, incapability, death, and increase in the use of insulin and diabetic symptoms. These illnesses underlie numerous illnesses such as dementia disorders and affect the entire process of treatment.

Diabetes, like other medical disorders, has a considerable interaction with depression and regarding that the incidence of depression in diabetic people is high, it is necessary to screen depression and to provide remedies such as education in order to improve the coping ability in these patients.

study is a library research. To find related articles and studies, reliable websites were searched (magiran, sciencedirect, ovid, springer, proquest), and in general, among 82 articles 74 ones were studied.

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Background and objective:

Little studies using a limited number of questionnaires cannot reflect the depth and complication of diabetic patients about self-care. However, using the qualitative research method, it is possible to find out the depth of patients’ experiences of this illness. The purpose of this study was to find individual and environmental obstacles which affect self-care on these patients and to investigate patients’ viewpoint of this disease.

Materials and Methods:

In this qualitative study, group interview and case interview have been used. This study was carried out in two phases and at the end of the interview patients were provided with necessary teaching about the principals of self-care.

Results:

In general, 5 categories of obstacles to self-care in type 2 diabetes were identified which include: physical obstacles, economical obstacles, social obstacles, educational obstacles, and psychic obstacles. Social, educational and psychic obstacles are in latter classes.

Conclusion:

The results of this study showed that a high percentage of patients with type 2 diabetes face serious obstacles in the way of self-care and the most numerous and important obstacles in their opinion are physical and economical obstacles. Considering that developing countries face a shortage of resources, dealing with physical obstacles can bring satisfaction to patients and on the other hand, dealing with these obstacles requires less cooperation from exterior organizations.

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Background & Objective: Dyslipidemia increases the risk of developing cardiovascular diseases in diabetic patients. Lipoprotein a, as a cholesterol carrier and competitive inhibitor of plasminogen in the blood coagulation system is considered an atherogenic factor which increases the risk of developing atherosclerosis in diabetic individuals. Based on previous studies, Barberry is thought to lower cholesterol and triglyceride levels. Since increased cholesterol level, especially Lipoprotein a, increases the risk of cardiovascular diseases in people with diabetes, the aim of this study was to evaluate serum levels of Lipoprotein (a) in diabetic rats treated with aqueous extract of Barberry. Method: In this experimental study, diabetes was induced in 15 mice by intraperitoneal injection of streptozotocin (STZ) and then they were treated orally for 14 days with liquid extract of the said plant in doses of 25 and 100 mg/kg. At the end of the treatment period, mice were kept fasted for 12 hours and then by heart phlebotomy, serum levels of Lipoprotein a, serum levels of glucose, triglycerides, total cholesterol, HDL and LDL were measured in normal and diabetic groups. The results were then analyzed using SPSS version 16, ANOVA and Tukey›s test. Results: Data analysis showed that the consumption of both oral doses of Berberis vulgaris (Barberry) in diabetic rats causes a significant reduction in serum levels of triglyceride, serum glucose and VLDL(P=0.01). The extract at both used doses also significantly reduced serum levels of lipoprotein (a) in treated diabetic rats (P=0.012). Conclusion: Oral administration of the aqueous extract of Berberis vulgaris (Barberry) is effective for reducing triglyceride and glucose levels in diabetic mice. Since Barberry lowers Lipoprotein (a) levels, it can be considered as an anti-atherogenic factor.